Product Publications :

Association between apoptotis and CD4(+)/CD8(+) T-lymphocyte ratio in aseptic loosening after total hip replacement.

Landgraeber S, von Knoch M, Löer F, Brankamp J, Tsokos M, Grabellus F, Schmid KW, Totsch M.
Int J Biol Sci. 2009;5(2):182-91. Epub 2009 Feb 3.

«…This was followed by incubation with the primary antibodies to caspase-3 cleaved (polyclonal antibody, dilution of 1:200; Zytomed Systems, Berlin, Germany),…"
«…CD4 (monoclonal antibody, dilution of 1:40; Zytomed Systems, Berlin, Germany)…»
«…Afterwards, a second incubation with Zytomed POLHRP-100 (brown) or POLAP-100 (red) as well as visualisation according to the manufacturer’s instructions (Zytomed Systems, Berlin, Germany) was performed…»
«…labeling with an immunhistochemical staining technique based on a horseradish peroxidase (HRP)-labeled polymer that is conjugated to secondary antibodies (ZytoChemPlus HRP Polymer Kit, Zytomed Systems) was done…»
«…Staining was completed by an incubation with 3,3´-diaminobenzidine + substrate-chromogen (Zytomed Systems), which results in a brown-colored precipitate at the antigen site…»
«…Second, CD4 or CD8 labeling was done with an alkaline phosphatase–labeled polymer (ZytoChemPlus AP Polymer Kit, Zytomed Systems)…»

TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens.

Schultz H, Kähler D, Branscheid D, Vollmer E, Zabel P, Goldmann T.
Diagn Pathol. 2008 Aug 12;3:35.

«…The primary antibody (anti-TKTL1; clone: JFC12T10; Zytomed Systems, Berlin) was incubated for 30 min. in a 1:100 dilution…»
«…We used an enzyme-polymersystem (ZytochemPlus HRP Polymer Kit, Zytomed Systems) for sensitive detection with permanent AEC (Zytomed Systems) as chromogen…»

Differential expression of microtubule-associated protein 2 in melanocytic skin lesions.

Gambichler T, Rotterdam S, Radkowski K, Altmeyer P, Kreuter A.
Am J Clin Pathol. 2009 May;131(5):710-4.

"...We aimed to study the expression of microtubuleassociated protein 2 (MAP-2) in different types of melanocytic skin lesions. Paraffin-embedded sections of 42 benign nevi (BN), 22 dysplastic nevi (DN), 45 superficial spreading melanomas (SSMs), and 15 subcutaneous melanoma metastases were immunohistologically assessed using the monoclonal mouse MAP-2ab antibody (Zytomed, Berlin, Germany)..."

Measles virus-induced block of transendothelial migration of T lymphocytes and infection-mediated virus spread across endothelial cell barriers.

Dittmar S, Harms H, Runkler N, Maisner A, Kim KS, Schneider-Schaulies J.
J Virol. 2008 Nov;82(22):11273-82. Epub 2008 Sep 3.

«… zona occludens-1 (ZO-1) (Zytomed Systems)…»
«… and by staining of tight-junction proteins such as ZO-1 with anti-ZO-1 (Zytomed Systems)…»

A novel nonobese diabetic/severe combined immunodeficient xenograft model for chronic lymphocytic leukemia reflects important clinical characteristics of the disease.

Dürig J, Ebeling P, Grabellus F, Sorg UR, Möllmann M, Schütt P, Göthert J, Sellmann L, Seeber S, Flasshove M, Dührsen U, Moritz T.
Cancer Res. 2007 Sep 15;67(18):8653-61.

«…Ki67 labeling with an immunohistochemical staining technique based on a horseradish peroxidase (HRP)–labeled polymer that is conjugated to secondary antibodies (ZytoChemPlus HRP Polymer Kit, Zytomed Systems) was done Staining was completed by an incubation with 3,3¶-diaminobenzidine + substrate-chromogen (Zytomed Systems), which results in a brown-colored precipitate at the antigen site…»

Expression of a Cu,Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of neuroblastoma cells to infectious injury.

Goos M, Zech WD, Jaiswal MK, Balakrishnan S, Ebert S, Mitchell T, Carrì MT, Keller BU, Nau R.
BMC Infect Dis. 2007 Nov 12;7:131.

«…or activated caspase-3 antibody [rabbit anti caspase-3 (cleaved), dilution 1:100, kindly donated by Zytomed Systems, Berlin, Germany] for 90 minutes… »
« …We thank Zytomed Systems, Berlin, Germany, for kindly providing antibodies directed against activated caspase-3. Maria T. CarriÅL was supported by PRIN 2005057598.»

BGLAP is expressed in pancreatic cancer cells and increases their growth and invasion.

Kayed H, Bekasi S, Keleg S, Michalski CW, Giese T, Friess H, Kleeff J.
Mol Cancer. 2007 Dec 28;6:83.

«…and incubated with the mouse monoclonal BGLAP antibody (ZYTOMED Systems GmbH, Berlin, Germany)…»

Epithelial endoplasmic reticulum stress and apoptosis in sporadic idiopathic pulmonary fibrosis.

Korfei M, Ruppert C, Mahavadi P, Henneke I, Markart P, Koch M, Lang G, Fink L, Bohle RM, Seeger W, Weaver TE, Guenther A.
Am J Respir Crit Care Med. 2008 Oct 15;178(8):838-46. Epub 2008 Jul 17.

«…immunohistochemistry was performed using the streptavidin-biotin-alkaline phosphatase (AP) method according to the manufacturer (ZytoChem-Plus AP Kit, Broad Spectrum; from Zytomed Systems, Berlin, Germany)…"
«…After three washes in PBS, a polyvalent secondary biotinylated antibody (rabbit, mouse, rat, guinea pig, provided by the ZytoChem-Plus AP Kit) was applied…»

Autonomous growth and hepatocarcinogenesis in transgenic mice expressing the p53 family inhibitor DNp73.

Tannapfel A, John K, Mise N, Schmidt A, Buhlmann S, Ibrahim SM, Pützer BM.
Carcinogenesis. 2008 Jan;29(1):211-8. Epub 2007 Nov 4.
«…cyclin D1 (Zytomed Systems, Berlin, Germany)…»

Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines.

Bock O, Höftmann J, Theophile K, Hussein K, Wiese B, Schlué J, Kreipe H.
Am J Pathol. 2008 Apr;172(4):951-60. Epub 2008 Mar 18.

«…Visualization was performed with the DAB Zytomed kit (DAB057; Zytomed Systems, Berlin, Germany)…»

Endothelial cells of human colorectal cancer and healthy colon reveal phenotypic differences in culture.

Schellerer VS, Croner RS, Weinländer K, Hohenberger W, Stürzl M, Naschberger E.
Lab Invest. 2007 Nov;87(11):1159-70. Epub 2007 Sep 17.

«… Slides were mounted with Aqueous Mount (Zytomed Systems, Berlin, Germany)…»

Glycodelin protein and mRNA is downregulated in human first trimester abortion and partially upregulated in mole pregnancy.

Toth B, Roth K, Kunert-Keil C, Scholz C, Schulze S, Mylonas I, Friese K, Jeschke U.
J Histochem Cytochem. 2008 May;56(5):477-85. Epub 2008 Feb 5.

«…The polyclonal antibody was investigated using the horseradish peroxidase-polymer system (Zytomed Systems; Berlin, Germany)…»
«… Antibodies used for immunohistochemistry/cytochemistry
Glycodelin         IgG rabbit         2.5 mg/ml     Zytomed
Glycodelin        A 6F2 IgG mouse     1 mg/ml     Zytomed…»

Proteome analysis of human substantia nigra in Parkinson's disease.

Werner CJ, Heyny-von Haussen R, Mall G, Wolf S.
Proteome Sci. 2008 Feb 14;6:8.

«…The applied antibody was directed against alpha-synuclein (Zytomed Systems, Berlin, Germany)…»


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